ADAMTS17 Antibody (3B7)

Western Blot: ADAMTS17 Antibody (3B7) [H00170691-M01] - ADAMTS17 monoclonal antibody (M01), clone 3B7 Analysis of ADAMTS17 expression in A-431.

Immunohistochemistry-Paraffin: ADAMTS17 Antibody (3B7) [H00170691-M01] - Analysis of monoclonal antibody to ADAMTS17 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 1.2 ug/ml.

Western Blot: ADAMTS17 Antibody (3B7) [H00170691-M01] - ADAMTS17 monoclonal antibody (M01), clone 3B7. Analysis of ADAMTS17 expression in NIH/3T3.

ELISA: ADAMTS17 Antibody (3B7) [H00170691-M01] - Detection limit for recombinant GST tagged ADAMTS17 is 0.3 ng/ml as a capture antibody.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC, IHC-P, S-ELISA
• Clone: 3B7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

ADAMTS17 Antibody (3B7) Summary

• Immunogen: ADAMTS17 (NP_620688, 543 a.a. ~ 650 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DGDWSPWGAWSMCSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDRLSPKKKGLLTAVVVDDKPCELYCSPLGKESPLLVAD
• Specificity: ADAMTS17 (3B7)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADAMTS17
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Sandwich ELISA
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ADAMTS17 Antibody (3B7)

• A disintegrin and metalloproteinase with thrombospondin motifs 17
• a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 17
• ADAM metallopeptidase with thrombospondin type 1 motif, 17
• ADAM-TS 17
• ADAM-TS17
• ADAMTS-17
• EC 3.4.24
• EC 3.4.24.-
• EC 3.4.24.80
• EC 3.4.24.82
• FLJ16363
• FLJ32769

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by ADAMTS19, another family member. The function of this protein has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ADAMTS17 Antibody (H00170691-M01)(2)

Publications using H00170691-M01

• Karoulias SZ, Beyens A, Balic Z et al. A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix Matrix Biol. Nov 11 2019 [PMID: 31726086] (WB, Human)
• Rickelt S, Hynes RO. Antibodies and methods for immunohistochemistry of extracellular matrix proteins Matrix Biol. May 3 2018 [PMID: 29730502] (IHC-P)

Bioinformatics

• Gene Symbol: ADAMTS17
• Entrez:
  • 170691(Human)
• OMIM:
  • 607511(Human)
• Uniprot:
  • NP_620688(Human)