eRF1 Products

Antibodies
eRF1 Antibody (2E3)
eRF1 Antibody (2E3)
NBP2-00740
Species: Hu, Mu, Rt, Ca, Mk
Applications: WB, Flow
Host: Mouse Monoclonal
eRF1 Antibody
eRF1 Antibody
NBP1-31113
Species: Hu, Mu, Rt, Bovine, Canine, Rabbit, Xenopus, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
eRF1 Antibody
eRF1 Antibody
NBP1-31144
Species: Hu, Mu, Bovine, Canine, Rabbit, Rat, Xenopus, Zebrafish, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
eRF1 Overexpression Lysate (N ...
eRF1 Overexpression Lysate (Native)
NBL1-10348
Applications: WB
Proteins
eRF1 Recombinant Protein
eRF1 Recombinant Protein
H00002107-P01
Species: Hu
Applications: WB, ELISA, PA
eRF1 Partial Recombinant Prot ...
eRF1 Partial Recombinant Protein
H00002107-Q01
Species: Hu
Applications: WB, ELISA, PA
eRF1 Recombinant Protein Anti ...
eRF1 Recombinant Protein Antigen
NBP2-38350PEP
Species: Hu
Applications: AC
RNAi
eRF1 RNAi
eRF1 RNAi
H00002107-R01
Species: Hu

Description

Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA; however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons (Frolova et al., 1994 [PubMed 7990965]).[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 2107
Alternate Names
  • sup45 (yeast omnipotent suppressor 45) homolog-like 1
  • SUP45L1
  • polypeptide chain release factor 1
  • Protein Cl1
  • eukaryotic peptide chain release factor subunit 1
  • Eukaryotic release factor 1
  • ERF1eRF1
  • TB3-1MGC111066
  • RF1ERF
  • D5S1995
  • eukaryotic translation termination factor 1

PTMs for eRF1

Learn more about PTMs related to eRF1.

Phosphorylation
Cleavage
Biotinylation
Methylation
Iodination

Bioinformatics Tool for eRF1

Discover related pathways, diseases and genes to eRF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.