CD11b Products

Antibodies
CD11b Antibody
CD11b Antibody
NB110-89474
Species: Hu, Mu, Rt, Bovine
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Proteins
CD11b Partial Recombinant Pro ...
CD11b Partial Recombinant Protein
H00003684-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
CD11b RNAi
CD11b RNAi
H00003684-R01
Species: Hu

Description

CD11b, also known as Integrin alpha M, is one half of the heterodimeric integrin alpha-M beta-2 molecule. This protein mediates inflammation by regulating leukocyte adhesion and migration and has been implicated in several immune processes such as phagocytosis, cell-mediated cytotoxicity, chemotaxis and cellular activation. CD11b is expressed on the surface of many leukocytes involved in the innate immune system, including monocytes, granulocytes, macrophages, and natural killer cells. CD11b antibodies are most useful for immunology studies.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Mouse
Product By Gene ID 3684
Alternate Names
  • Neutrophil adherence receptor
  • SLEB6
  • CD11b antigen
  • MAC1A
  • neutrophil adherence receptor alpha-M subunit
  • CR-3 alpha chain
  • macrophage antigen alpha polypeptide
  • CD11 antigen-like family member B
  • integrin alpha-M
  • Leukocyte adhesion receptor MO1
  • antigen CD11b (p170)
  • Cell surface glycoprotein MAC-1 subunit alpha
  • MO1A
  • MAC-1
  • CR3AMGC117044
  • CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide)
  • CD11b
  • integrin, alpha M (complement component 3 receptor 3 subunit)

Bioinformatics Tool for CD11b

Discover related pathways, diseases and genes to CD11b. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CD11b Blog Posts

Check out the latest blog posts on CD11b.
CD11b - More than a microglial marker
The protein CD11b has been implicated in the various adhesion-related interactions of cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. It is part of a heterodimer that consists of CD11b and CD18. It also modulates the...    Read more.
CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...    Read more.
Adhesion Receptor Molecule CD11b/c is the Point of Entry for many Infectious Diseases
Pathogenic microorganisms utilize a variety of cell surface receptors to gain entry into host cells and to bypass the natural defense mechanisms. One of the most prominent receptors used in this fashion is the leukocyte adhesion receptor CD11b/c. This...    Read more.
CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies
The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a...    Read more.
The CD11b Antibody: A Marker for Microglial Cells
Microglia are the resident macrophages of the central nervous system, and the first line of immune defense. Pioneering antibody research in the 1990's identified the Integrin beta 2 protein (also called ITGB2, complement receptor 3, CR3, CD18, and Mac...    Read more.
CD11b Expression, Leukocyte Adhesion and the Innate Immune System
CD11b is an integrin family member which pairs with CD18 to form the CR3 heterodimer. CD11b is expressed on the surface of many leukocytes including monocytes, neutrophils, natural killer cells, granulocytes and macrophages, as well as on 8% of spleen...    Read more.
Read more CD11b related blogs.