TLR9 Products

Antibodies
TLR9 Antibody (26C593.2)
TLR9 Antibody (26C593.2)
Species: Hu, Mu, Rt, Ca, Eq, Pm
Applications: WB, Simple Western, ELISA, Flow, Flow-IC, Func, ICC/IF, IHC, IHC-P, In vitro, IP, CyTOF-ready
Host: Mouse Monoclonal
TLR9 Antibody (2A4C6.2E5)
TLR9 Antibody (2A4C6.2E5)
NBP2-31150
Species: Mu
Applications: WB, IHC, IHC-P, ICC/IF (-)
Host: Rat Monoclonal
TLR9 Antibody
TLR9 Antibody
NBP1-77254
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
TLR9 Overexpression Lysate (N ...
TLR9 Overexpression Lysate (Native)
NBL1-16957
Applications: WB
Proteins
Recombinant Human TLR9 Protei ...
Recombinant Human TLR9 Protein
H00054106-Q01
Species: Hu
Applications: WB, ELISA, PA
TLR9 Blocking Peptide
TLR9 Blocking Peptide
NBP1-76680PEP
Species: Hu
Applications: AC
Recombinant Human TLR9 Protei ...
Recombinant Human TLR9 Protein
H00054106-G01
Species: Hu
RNAi
TLR9 RNAi
TLR9 RNAi
H00054106-R04
Species: Hu
Applications: RNAi, RNAi SP
TLR9 RNAi
TLR9 RNAi
H00054106-R03
Species: Hu
Applications: RNAi, RNAi SP
Reporter Cell Lines
Human TLR9 NF-kB/SEAP - (SEAP ...
Human TLR9 NF-kB/SEAP - (SEAPorter...
NBP2-26280
Applications: LA
Host: HEK293
Human TLR9 Stable Cell Line
Human TLR9 Stable Cell Line
NBP2-26272
Host: HEK293

Description

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TLR9 is strictly dependent on MyD88.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 54106
Alternate Names
  • CD289 antigen
  • CD289
  • toll-like receptor 9

Research Areas for TLR9

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity
Toll-Like Receptors

Bioinformatics Tool for TLR9

Discover related pathways, diseases and genes to TLR9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TLR9 Blog Posts

Check out the latest blog posts on TLR9.
Topics in CD11b: The innate immune response
Integrins are transmembrane receptors composed of alpha and beta chains, where beta-integrins are mainly expressed in leukocytes. Leukocytes are white blood cells that act in the immune system to defend our body against foreign pathogens.  Integrin...    Read more.
MHC Class I and the Herpes Simplex Virus
MHC molecules (also known as major histocompatibility complex molecules) assist in the presentation of antigens to T cells in order to eradicate foreign pathogens.  These molecules are highly polymorphic, meaning that they exist in multiple varian...    Read more.
The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...    Read more.
IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...    Read more.
TLR9: For Whom the Cell Tolls
The Toll-like receptor 9 (TLR9) protein, also known as CD289, belongs to the family of Toll-like receptor (TLR) proteins which play a large role in pathogen recognition and the activation of innate immunity. Scientists using TLR9 antibodies have found...    Read more.
TLR9: Tollgate to Immunity
Toll-like receptors (TLRs) play an essential role in the activation of innate immunity, and TLRs are expressed in a large number of immune cells as well as in epithelial cells. TLR9 recognizes synthetic oligodeoxynucleotides (ODN) containing unmethyla...    Read more.
TLR9, Infectious Disease and Cancer
Toll-like receptor 9 (TLR9) is a protein encoded by TLR9 gene in humans. It is also known as cluster of differentiation 289 (CD289) and is a member of TLR family. Proteins from TLR family are transmembrane proteins that expressed in both antigen-resen...    Read more.
TLR9 Antibodies in Immunity Research
Toll-like receptor 9 (TLR9) is a member of the toll-like receptor family that plays a key role in pathogen recognition and activation of innate immunity. Scientists using TLR9 antibodies have found the protein is highly conserved from Drosophila to hu...    Read more.
Read more TLR9 related blogs.