TLR9 Products

Antibodies
TLR9 Antibody (26C593.2) - BS ...
TLR9 Antibody (26C593.2) - BSA Free
Species: Hu, Mu, Rt, Ca, Eq, Pm, Pm
Applications: WB, Simple Western, DB, ELISA, Flow, Func, ICC/IF, IHC, IP, B/N, CyTOF-ready, Mycoplasma
Host: Mouse Monoclonal
ELISA Kits
Human TLR9 ELISA Kit (Chemilu ...
Human TLR9 ELISA Kit (Chemilumines...
NBP2-76638
Species: Hu
Applications: ELISA
Rat TLR9 ELISA Kit (Colorimet ...
Rat TLR9 ELISA Kit (Colorimetric)
NBP2-76577
Species: Rt
Applications: ELISA
Human TLR9 ELISA Kit (Colorim ...
Human TLR9 ELISA Kit (Colorimetric)
NBP2-76574
Species: Hu
Applications: ELISA
Proteins
Recombinant Mouse TLR9 Fc Chi ...
Recombinant Mouse TLR9 Fc Chimera ...
7960-TR
Species: Mu
Applications: Bioactivity
Formulation Catalog # Availability Price  
TLR9 Antibody Blocking Peptid ...
TLR9 Antibody Blocking Peptide
NBP1-76680PEP
Species: Hu
Applications: AC
TLR9 Antibody Blocking Peptid ...
TLR9 Antibody Blocking Peptide
NBP1-77254PEP
Species: Hu
Applications: AC

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID 54106
Alternate Names
  • CD289 antigen
  • CD289
  • TLR9
  • toll-like receptor 9

Research Areas for TLR9

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity

Related TLR9 Blog Posts

Check out the latest blog posts on TLR9.
Toll-like receptors in the intestinal epithelial cells
By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria ...    Read more.
Topics in CD11b: The innate immune response
Integrins are transmembrane receptors composed of alpha and beta chains, where beta-integrins are mainly expressed in leukocytes. Leukocytes are white blood cells that act in the immune system to defend our body against foreign pathogens.  Integrin...    Read more.
MHC Class I and the Herpes Simplex Virus
MHC molecules (also known as major histocompatibility complex molecules) assist in the presentation of antigens to T cells in order to eradicate foreign pathogens.  These molecules are highly polymorphic, meaning that they exist in multiple varian...    Read more.
The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...    Read more.
IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...    Read more.
TLR9: For Whom the Cell Tolls
The Toll-like receptor 9 (TLR9) protein, also known as CD289, belongs to the family of Toll-like receptor (TLR) proteins which play a large role in pathogen recognition and the activation of innate immunity. Scientists using TLR9 antibodies have found...    Read more.
TLR9: Tollgate to Immunity
Toll-like receptors (TLRs) play an essential role in the activation of innate immunity, and TLRs are expressed in a large number of immune cells as well as in epithelial cells. TLR9 recognizes synthetic oligodeoxynucleotides (ODN) containing unmethyla...    Read more.
TLR9, Infectious Disease and Cancer
Toll-like receptor 9 (TLR9) is a protein encoded by TLR9 gene in humans. It is also known as cluster of differentiation 289 (CD289) and is a member of TLR family. Proteins from TLR family are transmembrane proteins that expressed in both antigen-resen...    Read more.
TLR9 Antibodies in Immunity Research
Toll-like receptor 9 (TLR9) is a member of the toll-like receptor family that plays a key role in pathogen recognition and activation of innate immunity. Scientists using TLR9 antibodies have found the protein is highly conserved from Drosophila to hu...    Read more.
Read more TLR9 related blogs.