TGR5/GPBAR1 Antibody

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Summary
Product Discontinued
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    • Catalog Number
      NBP1-39749
    • Availability
      Product Discontinued

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TGR5/GPBAR1 Antibody Summary

Immunogen
GPBAR1 antibody was raised against synthetic peptide from human GPBAR1 / TGR5.
Epitope
aa302-322
Specificity
A portion of amino acids 300-350 of human BG37/TGR5
Predicted Species
Monkey (90%), Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
GPBAR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5-10 ug/ml
  • Western Blot 2-4 ug/ml
Reviewed Applications
Read 1 Review rated 4
using
NBP1-39749 in the following applications:

Publications
Read Publications using
NBP1-39749 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 22881598). Gorilla (100%); Gibbon, Monkey (90%); Hamster (86%); Marmoset (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TGR5/GPBAR1 Antibody

  • BG37
  • BG37hBG37
  • G protein-coupled bile acid receptor 1
  • GPBA
  • GPBAR1
  • GPCR19
  • GPR131
  • G-protein coupled bile acid receptor 1
  • G-protein coupled bile acid receptor BG37
  • G-protein coupled receptor GPCR19
  • M-BAR
  • M-BARhGPCR19
  • membrane bile acid receptor
  • Membrane-type receptor for bile acids
  • MGC40597
  • TGR5
  • TGR5GPCR

Background

GPBRA1 (G protein-coupled bile acid receptor 1) was identified by Takeda S (PMID:12044878) in 2002. This gene have 3 splice form, and group a member of the G protein-coupled receptor (GPCR) superfamily. GPBRA1 was bile acids receptor in the cell membrane, which regulated the signal pathway of the production of intracellular cAMP, activation of a MAP kinase, and internalization of the receptor. In addition, this receptor could suppression the functions of macrophage and regulation of energy homeostasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TGR5/GPBAR1 Antibody (NBP1-39749)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Mouse
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Review for TGR5/GPBAR1 Antibody (NBP1-39749) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using NBP1-39749:
Filter by Applications
WB
(1)
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Filter by Species
Mouse
(1)
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Images Ratings Applications Species Date Details
Western Blot TGR5/GPBAR1 NBP1-39749
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4
reviewed by:
Verified Customer
WB Mouse 12/02/2015
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Summary

ApplicationWestern Blot
Sample Testedmouse Myc-cap cells
SpeciesMouse
LotNBP1-39749

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FAQs for TGR5/GPBAR1 Antibody (NBP1-39749) (0)

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Secondary Antibodies

 

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Research Areas for TGR5/GPBAR1 Antibody (NBP1-39749)

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Blogs on TGR5/GPBAR1.

The TGR5 Receptor and metabolic disease
The bile acid-responsive G-protein-coupled receptor TGR5 is widely distributed across the human body - including the endocrine glands, adipocyte cells, muscles, immune organs, spinal cord, and the enteric nervous system. G protein coupled receptor...  Read full blog post.

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Recent Reviews

4
5
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4
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2
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1
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Verified Customer
12/02/2015
Application: WB
Species: Mouse

Bioinformatics

Gene Symbol GPBAR1
Uniprot