ZMPSTE24 Antibody [DyLight 650]

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Product Details

Summary
Reactivity Hu, Mu, Ze, PmSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

ZMPSTE24 Antibody [DyLight 650] Summary

Immunogen
A synthetic peptide made to an N-terminal portion of the human ZMPSTE24 protein sequence (between residues 1-100). [Swiss-Prot O75844]
Localization
Integral membrane, primarily ER
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ZMPSTE24
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This ZMPSTE24 antibody is useful for Western Blot, where a band is seen at ~54 kDa representing ZMPSTE24 protein.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, mouse and zebrafish. Predicted to react with primate based on 100% sequence homology.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ZMPSTE24 Antibody [DyLight 650]

  • zona pellucida binding protein 2
  • zona pellucida-binding protein 2
  • ZPBP-like protein
  • ZPBPLMGC41930

Background

ZMPSTE24 is a zinc metalloprotease involved in the post-translational processing of LMNA precursors. Mutations in ZMPSTE24 have been associated with human diseases, often due to the accumulation of LMNA precursors. It is possible that ZMPSTE24, due to its association with LMNA, plays some role in human ageing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ZMPSTE24 Antibody (NB100-2387C) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NB100-2387B
DyLight 488 Labeled NB100-2387G
DyLight 550 Labeled NB100-2387R
HRP Labeled NB100-2387H

Additional ZMPSTE24 Products

Bioinformatics Tool for ZMPSTE24 Antibody (NB100-2387C)

Discover related pathways, diseases and genes to ZMPSTE24 Antibody (NB100-2387C). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for ZMPSTE24 Antibody (NB100-2387C)

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Pathways for ZMPSTE24 Antibody (NB100-2387C)

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PTMs for ZMPSTE24 Antibody (NB100-2387C)

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Research Areas for ZMPSTE24 Antibody (NB100-2387C)

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Blogs on ZMPSTE24.

ZMPSTE24 Mutations, Lamin A Processing & Laminopathies
ZMPSTE24 (FACE-1, CAAX prenyl protease 1 homolog) is a membrane associated zinc metalloprotease of the peptidase M48A family. It's catalytic activity can be defined as the peptide bond hydrolyzed in the sequence -C-|-A-A-X in which C is an S-isoprenyl...  Read full blog post.

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Bioinformatics

Gene Symbol ZMPSTE24