ZMPSTE24 Products

Description

This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq]

Bioinformatics

Product By Gene ID	10269
Alternate Names	zona pellucida binding protein 2 zona pellucida-binding protein 2 ZPBP-like protein ZPBPLMGC41930

Research Areas for ZMPSTE24

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Angiogenesis
Cancer

Related ZMPSTE24 Blog Posts

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ZMPSTE24 Mutations, Lamin A Processing & Laminopathies ZMPSTE24 (FACE-1, CAAX prenyl protease 1 homolog) is a membrane associated zinc metalloprotease of the peptidase M48A family. It's catalytic activity can be defined as the peptide bond hydrolyzed in the sequence -C-|-A-A-X in which C is an S-isoprenyl...    Read more.

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