ZMPSTE24 Products

ZMPSTE24 Antibody
ZMPSTE24 Antibody
Species: Hu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ZMPSTE24 Antibody Blocking Pe ...
ZMPSTE24 Antibody Blocking Peptide
Species: Hu
Applications: AC
ZMPSTE24 Antibody Blocking Pe ...
ZMPSTE24 Antibody Blocking Peptide
Species: Hu
Applications: AC
Recombinant Human ZMPSTE24 GS ...
Recombinant Human ZMPSTE24 GST (N-...
Species: Hu
Applications: WB, ELISA, PA, AP


ZMPSTE24, also known as FACE1, is a zinc metalloprotease involved in the post-translational processing of Lamin A/C precursors. Specifically, ZMPSTE-24 proteolytically removes the C-terminal three residues of the farnesylated Lamin proteins.

FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.

Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.


Entrez Human
Uniprot Human
Product By Gene ID 10269
Alternate Names
  • zona pellucida-binding protein 2
  • ZPBP-like protein
  • ZPBPLMGC41930
  • zona pellucida binding protein 2

Research Areas for ZMPSTE24

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cytoskeleton Markers
Extracellular Matrix
Signal Transduction
Ubiquitin Proteasome Pathway

Bioinformatics Tool for ZMPSTE24

Discover related pathways, diseases and genes to ZMPSTE24. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related ZMPSTE24 Blog Posts

Check out the latest blog posts on ZMPSTE24.
ZMPSTE24 Mutations, Lamin A Processing & Laminopathies
ZMPSTE24 (FACE-1, CAAX prenyl protease 1 homolog) is a membrane associated zinc metalloprotease of the peptidase M48A family. It's catalytic activity can be defined as the peptide bond hydrolyzed in the sequence -C-|-A-A-X in which C is an S-isoprenyl...    Read more.
Read more ZMPSTE24 related blogs.