V2 Vasopressin R/AVPR2 Antibody Summary
Synthetic 15 amino acid peptide from C-terminus of human AVPR2.
Human AVPR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Immunohistochemistry-Paraffin 1:10 - 1:500
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Baboon (100%), Marmoset (87%), Panda (87%), Canine (80%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for V2 Vasopressin R/AVPR2 Antibody
- Antidiuretic hormone receptor
- arginine vasopressin receptor 2
- AVPR V2
- Renal-type arginine vasopressin receptor
- V2 Vasopressin R
- V2 VasopressinR
- vasopressin V2 receptor
The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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