Urotensin-2 Antibody (UII-9)

Product Discontinued

Urotensin-2 Antibody (UII-9) Summary

• Immunogen: Human Urotensin II
• Localization: Secreted
• Specificity: NB100-62132 detects Urotensin II (U-II), a cyclic heptapeptide that functions both as a potent vasoconstrictor and a neurotransmitter/neuromodulator. U-II circulates in the plasma as a zymogen, and is activated by the urotensin converting enzyme.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: UTS2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoassay

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for Urotensin-2 Antibody (UII-9)

• UCN2
• UII
• UIIPRO1068
• U-IIUrotensin II
• urotensin 2
• urotensin-2
• UrotensinII
• Urotensin-II
• UTS2

Background

Urotensin II is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UTS2
• Entrez:
  • 10911(Human)