UBR5/EDD Antibody [FITC]

• Reactivity: Hu, Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: FITC

UBR5/EDD Antibody [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: The immunogen for this product maps to a region between residue 2749 and 2799 of human E3 Ubiquitin Protein Ligase, HECT domain using the numbering given in entry NP_056986.2 (GeneID 51366).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: UBR5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP1-71802. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for UBR5/EDD Antibody [FITC]

• DD5
• E3 ubiquitin protein ligase, HECT domain containing, 1
• E3 ubiquitin-protein ligase, HECT domain-containing 1
• EC 6.3.2
• EC 6.3.2.-
• EDD
• EDD1
• EDD1E3 ubiquitin-protein ligase UBR5
• EDDE3 identified by differential display
• hHYD
• HYD
• HYDFLJ11310
• Hyperplastic discs protein homolog
• KIAA0896MGC57263
• progestin induced protein
• Progestin-induced protein
• ubiquitin protein ligase E3 component n-recognin 5
• ubiquitin-protein ligase
• UBR5

Background

EDD encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBR5