UBR5/EDD Antibody

ELISA: UBR5/EDD Antibody [34990002]

Product Discontinued

UBR5/EDD Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human EDD1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: UBR5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for UBR5/EDD Antibody

• DD5
• E3 ubiquitin protein ligase, HECT domain containing, 1
• E3 ubiquitin-protein ligase, HECT domain-containing 1
• EC 6.3.2
• EC 6.3.2.-
• EDD
• EDD1
• EDD1E3 ubiquitin-protein ligase UBR5
• EDDE3 identified by differential display
• hHYD
• HYD
• HYDFLJ11310
• Hyperplastic discs protein homolog
• KIAA0896MGC57263
• progestin induced protein
• Progestin-induced protein
• ubiquitin protein ligase E3 component n-recognin 5
• ubiquitin-protein ligase
• UBR5

Background

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for UBR5/EDD Antibody (34990002)(2)

Publications using 34990002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: UBR5
• Entrez:
  • 51366(Human)
• Uniprot:
  • O95071(Human)