SRCAP Recombinant Enzymes

• Reactivity: Hu
• Applications: NULL

SRCAP Recombinant Enzymes Summary

• Description: Human SRCAP (aa 2-3070) fused to 6xHis and FLAG-tag at the N-terminus. (Uniprot: Q6ZRS2-3)
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Enzymes
• Gene: SRCAP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • N/A

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for SRCAP Recombinant Enzymes

• domino homolog 1
• Domino homolog 2
• DOMO1
• EAF1
• EC 3.6.1
• EC 3.6.4.-
• FLJ44499
• KIAA0309helicase SRCAP
• Snf2-related CBP activator
• Snf2-related CREBBP activator protein
• Swi2/Snf2-related ATPase homolog, domino homolog 1
• SWR1Snf2-related CBP activator protein

Background

Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SRCAP