Snapin Antibody (809116) [Biotin]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 809116
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Biotin

Snapin Antibody (809116) [Biotin] Summary

• Immunogen: E. coli-derived recombinant human Snapin
  Met1-Lys136
  Accession # O95295
• Specificity: Detects human Snapin in direct ELISAs and human and mouse Snapin in Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SNAPIN
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Snapin Antibody (809116) [Biotin]

• SNAP-25-binding protein
• SNAP25BP
• SNAPAP
• SNAPAPSNARE-associated protein Snapin
• SNAP-associated proteinSNARE associated protein snapin
• Snapin
• Synaptosomal-associated protein 25-binding protein

Background

SNAPIN is a component of the SNARE complex of proteins that is required for synaptic vesicle docking and fusion. It may modulate a step between vesicle priming, fusion and calcium dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma membrane associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. It may also have a role in the mechanisms of SNARE mediated membrane fusion in non neuronal cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNAPIN