Snapin Antibody (809116) [Alexa Fluor® 750]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 809116
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

Snapin Antibody (809116) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human Snapin
  Met1-Lys136
  Accession # O95295
• Specificity: Detects human Snapin in direct ELISAs and human and mouse Snapin in Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Snapin Antibody (809116) [Alexa Fluor® 750]

• SNAP-25-binding protein
• SNAP25BP
• SNAPAP
• SNAPAPSNARE-associated protein Snapin
• SNAP-associated proteinSNARE associated protein snapin
• Snapin
• Synaptosomal-associated protein 25-binding protein

Background

Snapin (SNARE-associated protein) is an approximately 15 kDa, 136 amino acid vesicular phosphoprotein that contains a coiled-coil interacting domain. In neurons, it binds SNAP25 and RGS7 and regulates steps between synaptic vesicle docking and neurotransmitter release. In pancreatic beta cells, it mediates incretin-stimulated insulin secretion. In germ cells, it binds PUM2 and Nanos1 as a putative adaptor protein. Human Snapin shares 98% aa sequence identity with mouse and rat Snapin, while mouse and rat Snapin share 100% aa sequence identity with each other.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.