Serpin A11 Antibody (895842) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clone: 895842
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

Serpin A11 Antibody (895842) [Alexa Fluor® 350] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human SerpinA11
  Met1-Gly422
  Accession # Q86U17
• Specificity: Detects human SerpinA11 in ELISA and Western Blot.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin A11 Antibody (895842) [Alexa Fluor® 350]

• Antiproteinase-Like 2
• antitrypsin), member 11
• member 11
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• Serpin A11
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Background

Serpin A11 (serine proteinase inhibitor – clade A#11) is a 50-60 kDa secreted member of the serpin superfamily of protease inhibitors.  Serpins are the largest family of endogenous protease inhibitors, and target a wide variety of serine and cysteine proteases.  In general, members of this superfamily regulate multiple proteolytic cascades, and are particularly effective due to the fact that their inhibitory activities can be fine-tuned through the participation of discrete, non-serpin co-factors.  Serpin A11 gene expression is extremely high in normal liver, with lower levels detected in normal breast, breast tumor, and benign prostatic hyperplasia.  Human Serpin A11 is 422 amino acids (aa) in length, with four potential N-linked glycosylation sites, and shares 75% aa sequence identity with mouse Serpin A11.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.