SCAMP5 Antibody

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Western Blot: SCAMP5 Antibody [NB120-3432] - Analysis of rat brain extract.

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

SCAMP5 Antibody Summary

Immunogen
Synthetic Peptide: C N(217) Q P Q T Q Y S A T P N Y T Y S N(233)
Specificity
NB120-3432 immunizing peptide corresponds to amino acid residues 217-233 from rat SCAMP 5. This sequence is 94% conserved in mouse.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SCAMP5
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
Application Notes
WB: Detects an approx. 25 kDa protein representing SCAMP 5 from rat brain extract.

Reactivity Notes

Expected cross-reactivity with Mouse base on sequence homology.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SCAMP5 Antibody

  • DKFZp686L1799
  • hSCAMP5
  • MGC24969
  • Sc5
  • secretory carrier membrane protein 5
  • secretory carrier-associated membrane protein 5

Background

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SCAMP5
Entrez