A synthetic peptide as a part of human, rat, mouse Rho-related GTP-binding protein RhoB (ARH6, ARHB, H6) conjugated to an immunogenic carrier protein was used as the immunogen.
subcellular location: late endosome membrane; lipid-anchor. cell membrane; lipid-anchor. nucleus. note=late endosomal membrane (geranylgeranylated form). plasma membrane (farnesylated form). also detected at the nuclear margin and in the nucleus.
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After reconstituted, glycerol (1:1) may be added for additional stability.
Alternate Names for RhoB Antibody
ARHBAplysia RAS-related homolog 6
oncogene RHO H6
ras homolog gene family, member B
Rho cDNA clone 6
rho-related GTP-binding protein RhoB
Mediates apoptosis in neoplastically transformed cells after dna damage. not essential for development but affects cell adhesion and growth factor signaling in transformed cells. plays a negative role in tumorigenesis as deletion causes tumor formation. involved in intracellular protein trafficking of a number of proteins. targets pkn1 to endosomes and is involved in trafficking of the egf receptor from late endosomes to lysosomes. also required for stability and nuclear trafficking of akt1/akt which promotes endothelial cell survival during vascular development.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for RhoB Antibody (NBP1-03484). (Showing 1 - 1 of 1 FAQ).
I just ordered this antibody and when I opened the vial, I found it contains of something a large like impurity visibly. Do you know what this is?
This product is supplied as lyophilized powder. You will need to centrifuge the vial and reconstitute the lyophilized antibody in 0.5ml of sterile dH2O. We also recommend that you centrifuge to remove any insoluble material after reconstitution. When reconstituting, glycerol (1:1) may be added for an additional stability.