RGS3 Antibody

Western Blot: RGS3 Antibody [NB120-2564] - Western blot analysis of RGS3 in transfected HEK293 cells (right lane). The left lane is mock control.

Product Discontinued

RGS3 Antibody Summary

• Description: This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab2564)
• Immunogen: E. coli expressed human RGS 3 (amino acids 401-519).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RGS3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2), 1% BSA, 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Affinity purified

Alternate Names for RGS3 Antibody

• C2PA
• FLJ20370
• FLJ31516
• FLJ90496
• PDZ-RGS3
• regulator of G-protein signaling 3
• regulator of G-protein signalling 3
• RGP3

Background

RGS 3 (Regulator of G protein Signaling 3) is a 519 residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase activating protein (GAP). RGS 3 negatively regulates the activation of Gialpha and G alpha q. A truncated RGS 3 (RGS 3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS 3T may be localized in the nucleus and RGS 3 is found in cytoplasm. Translocation to the membrane is important for the RGS proteins to interact with heterotrimeric G proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RGS3 Antibody (NB120-2564)(1)

Publication using NB120-2564

• Mueller F-J, Serobyan N, Schraufstatter I U et al. Adhesive Interactions Between Human Neural Stem Cells Inflamed Human Vascular Endothelium Are Mediated by Integrins. Stem Cells,; 24: 2367 - 23721. 2006-11-01 [PMID: 17071855]

Bioinformatics

• Gene Symbol: RGS3
• Uniprot:
  • P49796(Human)