Applications: WB, ELISA
Host: Mouse Monoclonal
Host: Rabbit Polyclonal
Applications: WB, ELISA, AP
RGS 3 (Regulator of G protein Signaling 3) is a 519 residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase activating protein (GAP). RGS 3 negatively regulates the activation of Gialpha and G alpha q. A truncated RGS 3 (RGS 3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS 3T may be localized in the nucleus and RGS 3 is found in cytoplasm. Translocation to the membrane is important for the RGS proteins to interact with heterotrimeric G proteins.
Research Areas for RGS3
Find related products by research area and learn more about each of the different research areas below.Signal Transduction
Bioinformatics Tool for RGS3
Discover related pathways, diseases and genes to RGS3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.