PTPN7 Antibody (AFPK32)

Immunohistochemistry-Paraffin: PTPN7 Antibody (AFPK32) [NBP2-11537] - Analysis of anti-PTPN7 antibody with human spleen at dilution 1:200.

Immunohistochemistry-Paraffin: PTPN7 Antibody (AFPK32) [NBP2-11537] - Analysis of anti-PTPN7 antibody with human tonsil at dilution 1:200.

Product Discontinued

PTPN7 Antibody (AFPK32) Summary

• Immunogen: Recombinant human PTPN7 purified from E. coli.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTPN7
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:200
  • Western Blot 1:5000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: HEPES, 0.01% BSA, 0.15M NaCl and 50% Glycerol
• Preservative: 0.03% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for PTPN7 Antibody (AFPK32)

• BPTP-4
• FLJ18703
• HEPTPnonreceptor-type, stress induced
• LPTP
• protein tyrosine phosphatase, non-receptor type 7
• PTPN7
• tyrosine-protein phosphatase non-receptor type 7

Background

PTPN7 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPN7
• Entrez:
  • 5778(Human)
• Uniprot:
  • P35236(Human)