PTPN7 Products

Description

PTPN7 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	5778 Human
Uniprot	AAH01746 Human NM_002832 Human NM_080588 Human NP_002823 Human NP_542155.1 Human P35236 Human
Product By Gene ID	5778
Alternate Names	BPTP-4 FLJ18703 HEPTPnonreceptor-type, stress induced LPTP protein tyrosine phosphatase, non-receptor type 7 tyrosine-protein phosphatase non-receptor type 7

Research Areas for PTPN7

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Cancer
Phospho-Specific