PTGER1 Antibody

Immunohistochemistry-Paraffin: PTGER1 Antibody [NLS962] - Anti-PTGER1 / EP1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: PTGER1 Antibody [NLS962] - Analysis of anti-PTGER1 / EP1 antibody with human kidney, renal tubules at dilution 13 ug/ml.

Immunohistochemistry-Paraffin: PTGER1 Antibody [NLS962] - Anti-PTGER1 / EP1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

PTGER1 Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human PTGER1 / EP1.
• Specificity: Human PTGER1 / EP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Canine (94%), Hamster (94%), Primate (94%), Monkey (94%), Bovine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTGER1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5-10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Marmoset (94%), Mouse (81%), Rat (81%), Bat (81%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PTGER1 Antibody

• EP1
• PGE receptor EP1 subtype
• PGE receptor, EP1 subtype
• PGE2 receptor EP1 subtype
• prostaglandin E receptor 1 (subtype EP1), 42kD
• prostaglandin E receptor 1 (subtype EP1), 42kDa
• prostaglandin E receptor 1, subtype EP1
• prostaglandin E2 receptor EP1 subtype
• Prostanoid EP1 receptor
• PTGER1

Background

Prostaglandin E receptor EP1 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP2, EP3, and EP4), it mediates the diverse biological effects of prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, cervical and colon cancer, induction of labor, control of blood pressure, bone resorption, and asthma. Prostaglandin E receptor EP1 expression has been documented in kidney and kidney vessels. ESTs have been primarily isolated from kidney, pancreas, and thymus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTGER1
• Entrez:
  • 5731(Human)
• Uniprot:
  • P34995(Human)