PTGER1 Antibody (1014918) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: IHC
• Clone: 1014918
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

PTGER1 Antibody (1014918) [Alexa Fluor® 647] Summary

• Immunogen: Synthetic peptide containing human PTGER1
  Accession # P34995
• Specificity: Detects human PTGER1 in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PTGER1 Antibody (1014918) [Alexa Fluor® 647]

• EP1
• PGE receptor EP1 subtype
• PGE receptor, EP1 subtype
• PGE2 receptor EP1 subtype
• prostaglandin E receptor 1 (subtype EP1), 42kD
• prostaglandin E receptor 1 (subtype EP1), 42kDa
• prostaglandin E receptor 1, subtype EP1
• prostaglandin E2 receptor EP1 subtype
• Prostanoid EP1 receptor
• PTGER1

Background

PTGER1 is a one of four EP₁ receptors for PGE2 which is mediated by G(q) proteins.  PTGER1 may play a role as an important modulator of renal functions.  It has also been detected in mast cells, pulmonary veins, keratinocytes, myometrium and colon smooth muscle. EP₁ expression has also frequently been seen in human breast cancers.  Nuclear expression of EP₁ correlates with good prognosis markers like node negative status and PR expression. Animal model studies have implicated EP₁ in various physiological and pathological responses however expression in humans appears to be more limited. EP₁ receptor antagonists have been studied clinically primarily to treat hyperalgesia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.