PRPF8 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu, Mu
• Applications: WB, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

PRPF8 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 1825 and 1875 of human Pre-mRNA-Processing Factor 8 using the numbering given in entry NP_006436.3 (GeneID 10594).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRPF8
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PRPF8 Antibody [mFluor Violet 450 SE]

• apoptosis-regulated protein 1
• apoptosis-regulated protein 2
• p220
• precursor mRNA processing protein
• pre-mRNA-processing-splicing factor 8
• PRP8 homolog
• PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
• PRP8 pre-mRNA processing factor 8 homolog (yeast)
• Prp8
• PRP8,220 kDa U5 snRNP-specific protein
• PRPC8HPRP8
• RP13
• Splicing factor Prp8
• U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p

Background

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRPF8