ProSAPiP1 Antibody - BSA Free

Western Blot: ProSAPiP1 Antibody [NBP1-77369] - SK-N-SH cell lysate with Prosapip1 antibody at 1 ug/mL.

Immunohistochemistry: ProSAPiP1 Antibody - BSA Free [NBP1-77369] - Immunohistochemistry of ProSAPiP1 in rat brain tissue with ProSAPiP1 antibody at 2.5 u/mL.

Immunocytochemistry/ Immunofluorescence: ProSAPiP1 Antibody - BSA Free [NBP1-77369] - Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

ProSAPiP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ProSAPiP1 Antibody - BSA Free (NBP1-77369) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1. The immunogen is located within amino acids 590 - 640 of Prosapip1. Amino Acid Squence: RRVWLEEKEKVIEYQK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LZTS3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  ProSAPiP1 Peptide (NBP1-77369PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for ProSAPiP1 Antibody - BSA Free

• KIAA0552
• proline rich synapse associated protein interacting protein 1
• proSAP-interacting protein 1
• ProSAPiP1 protein

Background

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LZTS3
• Uniprot:
  • NP_055546(Human)