PP2C beta/PPM1B Antibody (k1B1)

Product Discontinued

PP2C beta/PPM1B Antibody (k1B1) Summary

• Immunogen: Recombinant human PPM1B (288-479aa) purified from E. coli
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PPM1B
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Flow Cytometry
  • Western Blot 1:1000-1:3000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for PP2C beta/PPM1B Antibody (k1B1)

• EC 3.1.3.16
• MGC21657
• PP2C beta
• Pp2c2
• PP2CB
• PP2C-beta
• PP2C-beta-X
• PP2CBmagnesium-dependent, beta isoform
• PPM1B
• protein phosphatase 1B
• Protein phosphatase 2C isoform beta
• protein phosphatase 2C-like protein
• protein phosphatase, Mg2+/Mn2+ dependent, 1B

Background

Protein phosphatase 1B (PPM1B) is a member of the PP2C family of serine/threonine protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPM1B
• Uniprot:
  • NP_808908(Human)