Potassium Channel Kv3.1 Antibody

Images

 
Western Blot: Potassium Channel Kv3.1 Antibody [NBP1-42819] - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ca, RbSpecies Glossary
Applications WB, B/N, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Potassium Channel Kv3.1 Antibody Summary

Immunogen
Synthetic peptide made to an internal portion of rat Kv3.1 (within residues 350-400). [Swiss-Prot# P25122]
Localization
Membrane; Multi-pass membrane protein.
Specificity
Does not cross-react with Kv1.2 or Kv1.3.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Blocking/Neutralizing 50-200 molar excess
  • Immunoprecipitation 1:10-1:500
Application Notes
This Kv3.1 antibody is useful for Blocking/Neutralizing, Western blot and Immunoprecipitation. In WB a band can be seen at ~110 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-42819 in the following applications:

  • WB
    2 publications

Reactivity Notes

Human, mouse, rat, rabbit, bovine, canine and other vertebrates.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Potassium Channel Kv3.1 Antibody

  • FLJ41162
  • FLJ42249
  • FLJ43491
  • KCNC1
  • KV3.1
  • KV4
  • MGC129855
  • NGK2
  • Potassium Channel Kv3.1
  • potassium voltage-gated channel subfamily C member 1
  • potassium voltage-gated channel, Shaw-related subfamily, member 1
  • voltage-gated potassium channel protein KV3.1
  • Voltage-gated potassium channel subunit Kv3.1
  • Voltage-gated potassium channel subunit Kv4

Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Potassium Channel Kv3.1 Antibody (NBP1-42819)(2)

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 1 application: WB.


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(2)
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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-42819AF405
Alexa Fluor 488 Labeled NBP1-42819AF488
Alexa Fluor 647 Labeled NBP1-42819AF647
Alexa Fluor 700 Labeled NBP1-42819AF700
Biotin Labeled NBP1-42819B
DyLight 405 Labeled NBP1-42819V
DyLight 488 Labeled NBP1-42819G
DyLight 550 Labeled NBP1-42819R
DyLight 650 Labeled NBP1-42819C
HRP Labeled NBP1-42819H

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Bioinformatics

Gene Symbol KCNC1
Entrez
Uniprot