p38 delta/SAPK4 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

p38 delta/SAPK4 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: E. coli-derived recombinant human p38δ
  Accession # O15264
• Specificity: Detects endogenous human p38δ. Mouse and rat p38δ reactivity has not been demonstrated but is likely due to their high homology with human p38δ. This antibody does not detect recombinant p38 alpha , p38 beta or p38 gamma in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MAPK13
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for p38 delta/SAPK4 Antibody [mFluor Violet 450 SE]

• EC 2.7.11
• EC 2.7.11.24
• MAP kinase 13
• MAPK 13
• MAPK13
• MGC99536
• mitogen-activated protein kinase 13
• Mitogen-activated protein kinase p38 delta
• p38 delta
• p38delta
• PRKM13
• SAPK4MAP kinase p38 delta
• Stress-activated protein kinase 4

Background

SAPK4 is encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAPK13