Recombinant Human p38 beta/MAPK11 Protein

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SDS-Page: Recombinant p38 beta/MAPK11 Protein [NBP1-99507]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE, HPLC
Concentration
0.1 mg/ml

Order Details

Recombinant Human p38 beta/MAPK11 Protein Summary

Description
Recombinant protein for Human p38 beta/MAPK11

Source:Baculovirus (Sf9 insect cells)
Amino Acid Sequence:(NM_002751)

Source
Sf 9 (baculovirus)
Protein/Peptide Type
Biologically Active Protein
Gene
MAPK11
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Application Notes
Specific activity: The specific activity of P38BETA was determined to be 123 nmol /min/mg as per activity assay protocol.
Theoretical MW
71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
50mM Tris-HCl, pH 7.5, and 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol
Concentration
0.1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human p38 beta/MAPK11 Protein

  • EC 2.7.11
  • EC 2.7.11.24
  • MAP kinase 11
  • MAP kinase p38 beta
  • MAPK 11
  • MAPK11
  • mitogen-activated protein kinase 11
  • Mitogen-activated protein kinase p38 beta
  • mitogen-activated protein kinase p38-2
  • p38 beta
  • p38b
  • p38Beta
  • P38BETA2
  • PRKM11
  • SAPK2B
  • SAPK2p38-2P38B
  • Stress-activated protein kinase 2
  • stress-activated protein kinase-2
  • stress-activated protein kinase-2b

Background

p38-Beta is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38-Beta is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol MAPK11
Entrez