P2X1/P2RX1 Antibody

Western Blot: P2X1/P2RX1 Antibody [NBP3-03143] - Analysis of extracts of various cell lines, using P2x1/P2Rx1 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Kit

Product Discontinued

P2X1/P2RX1 Antibody Summary

• Immunogen: A synthetic peptide of human P2X1/P2RX1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: P2RX1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS with 50% glycerol, pH7.3.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for P2X1/P2RX1 Antibody

• ATP receptor
• P2RX1
• P2X purinoceptor 1
• P2X receptor, subunit 1
• P2X1
• P2X1P2X1 receptor
• P2XMR
• purinergic receptor P2X, ligand-gated ion channel, 1
• Purinergic receptor

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: P2RX1