p18INK4c/CDKN2C Antibody

Western Blot: p18INK4c/CDKN2C Antibody [H00001031-B02P] - Analysis of CDKN2C expression in transfected 293T cell line by CDKN2C polyclonal antibody. Lane 1: CDKN2C transfected lysate(18.48 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: p18INK4c/CDKN2C Antibody [H00001031-B02P] - Analysis of purified antibody to CDKN2C on HeLa cell. (antibody concentration 10 ug/ml)

Product Discontinued

p18INK4c/CDKN2C Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CDKN2C (NP_001253.1, 1 a.a. - 168 a.a.) full-length human protein. MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CDKN2C
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: It has been used for WB, Functional and IF.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for p18INK4c/CDKN2C Antibody

• CDK6 inhibitor p18
• CDKN2C
• CDKN6
• cyclin-dependent inhibitor
• cyclin-dependent kinase 4 inhibitor C
• Cyclin-dependent kinase 6 inhibitor
• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
• INK4Ccyclin-dependent kinase 6 inhibitor p18
• p18
• p18INK4c
• p18-INK4C
• p18-INK6

Background

p18 INK4c is a specific inhibitor of cdk4 / cdk6 (interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels found in skeletal muscle. p18 INK4c is also found in pancreas and heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDKN2C
• Uniprot:
  • NP_001253.1(Human)