p18INK4c/CDKN2C Antibody

ELISA: p18INK4c/CDKN2C Antibody [29240002]

Product Discontinued

p18INK4c/CDKN2C Antibody Summary

• Immunogen: This antibody is specific for the C Terminus Region of the target protein.
• Specificity: This product is specific for Human CDKN2C.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CDKN2C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: This antibody is useful in ELISA.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for p18INK4c/CDKN2C Antibody

• CDK6 inhibitor p18
• CDKN2C
• CDKN6
• cyclin-dependent inhibitor
• cyclin-dependent kinase 4 inhibitor C
• Cyclin-dependent kinase 6 inhibitor
• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
• INK4Ccyclin-dependent kinase 6 inhibitor p18
• p18
• p18INK4c
• p18-INK4C
• p18-INK6

Background

p18 INK4c is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for p18INK4c/CDKN2C Antibody (29240002)(2)

Publications using 29240002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: CDKN2C
• Entrez:
  • 1031(Human)
• Uniprot:
  • P42773(Human)