p18INK4c/CDKN2C Antibody (OTI2E1)

Western Blot: p18INK4c/CDKN2C Antibody (2E1) [NBP2-46229] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDKN2C .

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI2E1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

p18INK4c/CDKN2C Antibody (OTI2E1) Summary

• Immunogen: Full length human recombinant protein of human CDKN2C (NP_001253) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDKN2C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:2000
• Theoretical MW: 17.9 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for p18INK4c/CDKN2C Antibody (OTI2E1)

• CDK6 inhibitor p18
• CDKN2C
• CDKN6
• cyclin-dependent inhibitor
• cyclin-dependent kinase 4 inhibitor C
• Cyclin-dependent kinase 6 inhibitor
• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
• INK4Ccyclin-dependent kinase 6 inhibitor p18
• p18
• p18INK4c
• p18-INK4C
• p18-INK6

Background

p18 INK4c is a specific inhibitor of cdk4 / cdk6 (interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels found in skeletal muscle. p18 INK4c is also found in pancreas and heart.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDKN2C