OSBP2 Antibody

Western Blot: OSBP2 Antibody [NBP2-19635] - Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.

Immunohistochemistry-Paraffin: OSBP2 Antibody [NBP2-19635] - Analysis of paraffin-embedded human colon carcinoma, using OSBP2 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Product Discontinued

OSBP2 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human OSBP2. The exact sequence is proprietary.
• Localization: Membrane; Peripheral membrane protein
• Predicted Species: Mouse (92%), Rat (93%), Bovine (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OSBP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 101 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for OSBP2 Antibody

• ORP4ORP-4KIAA1664Oxysterol-binding protein-related protein 4
• OSBPL1
• OSBPL4
• OSBP-related protein 4
• oxysterol binding protein 2
• oxysterol binding protein-like 1
• oxysterol binding protein-related protein 4
• oxysterol-binding protein 2

Background

Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: OSBP2
• Uniprot:
  • Q969R2(Human)