Neuromedin BR/NMBR Antibody (466501) [DyLight 650]

• Reactivity: Hu
• Applications: IHC
• Clone: 466501
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

Neuromedin BR/NMBR Antibody (466501) [DyLight 650] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human Neuromedin B R/NMBR
  Accession # NP_002502
• Specificity: Detects human Neuromedin B R/NMBR in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: NMBR
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Neuromedin BR/NMBR Antibody (466501) [DyLight 650]

• Neuromedin B R
• neuromedin B receptor
• Neuromedin BR
• neuromedin-B receptor
• Neuromedin-B-preferring bombesin receptor
• NMBR
• NMB-R

Background

The neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NMBR