MX2 Antibody

Images

 
Western Blot: MX2 Antibody [NBP1-81018] - Analysis in control (vector only transfected HEK293T lysate) and mX2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: MX2 Antibody [NBP1-81018] - Staining of human skin shows strong cytoplasmic positivity in epidermal cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

MX2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PYRRRSQFSSRKYLKKEMNSFQQQPPPFGTVPPQMMFPPNWQGAEKDAAFLAKDFNFLTLNNQPPPGNRSQPRAMG
Specificity
Specificity of human MX2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MX2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.4 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Theoretical MW
82 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
MX2 Recombinant Protein Antigen (NBP1-81018PEP)
Publications
Read Publications using
NBP1-81018 in the following applications:

Reactivity Notes

Reactivity reported in scientific literature (PMID: 25043006)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MX2 Antibody

  • human interferon-regulated resistance GTP-binding protein MXB10Interferon-regulated resistance GTP-binding protein MxB
  • interferon-induced GTP-binding protein Mx2
  • MXB
  • myxovirus (influenza virus) resistance 2 (mouse)
  • myxovirus (influenza) resistance 2, homolog of murine
  • Myxovirus resistance protein 2
  • p78-related protein
  • second interferon-induced protein p78

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MX2 Antibody (NBP1-81018)(8)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ICC/IF, WB.


Filter By Application
ICC/IF
(1)
WB
(5)
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Filter By Species
Human
(5)
All Species
Showing Publications 1 - 8 of 8.
Publications using NBP1-81018 Applications Species
Martinez-Lopez A, Martin-Fernandez M, Buta S et al. SAMHD1 deficient human monocytes autonomously trigger type I interferon Mol. Immunol. Aug 8 2018 [PMID: 30099227] (WB, Human) WB Human
Kane M, Rebensburg SV, Takata MA et al. Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2 Elife Aug 7 2018 [PMID: 30084827] (ICC/IF, Human) ICC/IF Human
Sali TM, Pryke KM, Abraham J et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog 2015 Dec [PMID: 26646986] (WB, Human) WB Human
Sandler NG, Bosinger SE, Estes JD et al. Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature 2014 Jul 31 [PMID: 25043006]
Wei W, Guo H, Ma M et al. Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations. EBioMedicine. 2016 Apr 17
Wei W, Guo H, Ma M et al. Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations. EBioMedicine 2016 Jun [PMID: 27428433] (WB) WB
Opp S, Vieira D, Schulte B et al. MxB is not responsible for the block to HIV-1 observed in IFN-alpha-treated cells. J. Virol. 2015 Dec 30 [PMID: 26719253] (WB, Human) WB Human
Kane M, Yadav SS, Bitzegeio J et al. MX2 is an interferon-induced inhibitor of HIV-1 infection. Nature. 2013 Oct 24 [PMID: 24121441] (WB, Human) WB Human

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for MX2 Antibody (NBP1-81018). (Showing 1 - 1 of 1 FAQs).

  1. What is the concentration of this product?
    • The concentration of our product NBP1-81018 Lot A83265 is 0.2mg/ml.

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Bioinformatics

Gene Symbol MX2
Entrez
Uniprot