MEX3D Antibody


Western Blot: MEX3D Antibody [NBP1-77332] - MDA-MB-361 cell lysate with MEX3D antibody at (A) 1 ug/ml and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: MEX3D Antibody [NBP1-77332] - Immunofluorescence of rkhd1 in human small intestine tissue with rkhd1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: MEX3D Antibody [NBP1-77332] - Human small intestine tissue with MEX3D antibody at 2.5 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P, IF
1 mg/ml

Order Details

MEX3D Antibody Summary

Antibody was raised against a 15 amino acid peptide from near the center of human Rkhd1.
Immunogen affinity purified
Innovator's Reward
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified


Reactivity Notes


Alternate Names for MEX3D Antibody

  • KIAA2031Tino
  • mex-3 homolog D (C. elegans)
  • OK/SW-cl.4
  • ring finger (C3HC4 type) and KH domain containing 1
  • ring finger and KH domain containing 1
  • RING finger and KH domain-containing protein 1
  • RING finger protein 193
  • RNA-binding protein MEX3D
  • RNF193MEX-3D
  • TINObcl-2 ARE RNA binding protein


Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Additional MEX3D Antibody Products

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Contact Information

Product PDFs


Gene Symbol MEX3D

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