MAT2A Antibody (3A2) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 3A2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

MAT2A Antibody (3A2) [Janelia Fluor® 669] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Recombinant human MAT2A (1-395aa) purified from E. coli (NP_005902).
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAT2A
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP1-28605. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MAT2A Antibody (3A2) [Janelia Fluor® 669]

• AdoMet synthase 2
• AMS2
• EC 2.5.1.6
• MAT 2
• MAT2A
• MATA2
• MATA2SAMS2adoMet synthetase 2
• MATII
• MAT-II
• Methionine adenosyltransferase 2
• Methionine adenosyltransferase II
• methionine adenosyltransferase II, alpha
• S-adenosylmethionine synthase isoform type-2
• S-adenosylmethionine synthetase isoform type-2
• SAMS2

Background

MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAT2A