LSM2 Antibody (1G7) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 1G7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 594

LSM2 Antibody (1G7) [Alexa Fluor® 594] Summary

• Immunogen: Recombinant human LSm2 (1-95aa) purified from E. coli
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: LSM2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for LSM2 Antibody (1G7) [Alexa Fluor® 594]

• C6orf28chromosome 6 open reading frame 28
• G7b
• LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
• Protein G7b
• Small nuclear ribonuclear protein D homolog
• snRNP core Sm-like protein Sm-x5
• snRNP
• U6 snRNA-associated Sm-like protein LSm2
• YBL026W

Background

LSM2 is a member of the LSm family of RNA-binding proteins. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2 complex, which is involved in splicing of nuclear mRNAs. LSM2 associates with multiple snRNP complexes containing the U6 snRNA It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LSM2