Liprin alpha 1 Antibody

Images

 
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-PPFIA1)

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated

Order Details

Liprin alpha 1 Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 310a.a. to 360a.a. from Liprin-alpha-1(a 1202a.a. long protein)
Localization
Cytoplasm. Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.
Specificity
Liprin-alpha-1
Clonality
Polyclonal
Host
Chicken
Gene
PPFIA1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for Liprin alpha 1 Antibody

  • FLJ42630
  • FLJ43474
  • LAR-interacting protein 1
  • LIP.1
  • LIP-1
  • LIP1FLJ41337
  • LIPRIN
  • Liprin-alpha1
  • liprin-alpha-1
  • MGC26800
  • Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-1
  • protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 1
  • PTPRF-interacting protein alpha-1

Background

This protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane. possibly regulating their interaction with the extracellular environment and their association with substrates.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PPFIA1
Entrez
Uniprot