Liprin alpha 1 Products

Description

Liprin alpha 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane. possibly regulating their interaction with the extracellular environment and their association with substrates.

Bioinformatics

Entrez	8500 Human
Uniprot	NM_177423 Human NP_003617 Human
Product By Gene ID	8500
Alternate Names	FLJ42630 FLJ43474 LAR-interacting protein 1 LIP.1 LIP-1 LIP1FLJ41337 LIPRIN Liprin-alpha1 liprin-alpha-1 MGC26800 Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 1 PTPRF-interacting protein alpha-1

Diseases related to Liprin alpha 1

Discover more about diseases related to Liprin alpha 1.

Tissue Adhesions
Neoplasms
Carcinoma
Malignant Squamous Cell Neoplasm
Malignant Neoplasms
Head And Neck Carcinoma
Neoplasm Metastasis
Nervousness
Cell Invasion
Malignant Neoplasm Of Breast
Tumor Angiogenesis
Mammary Neoplasms
Laryngeal Neoplasm
Protrusion
Colonic Neoplasms
Carcinogenesis
Laryngeal Squamous Cell Carcinoma
Metastatic Malignant Neoplasm To The Lymph Node
Glioma
Malignant Tumor Of Colon

Pathways for Liprin alpha 1

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Localization
Cell Motility
Axon Guidance
Rna Interference
Cell Adhesion
Cell Migration
Mammary Gland Development
Cell Proliferation
Gland Development
Dendrite Development
Synaptic Transmission
Angiogenesis
Pathogenesis
Transport
Synapse Maturation
Regulation Of Dendrite Development
Programmed Cell Death
Immune Response
Cell Cycle
Regulation Of Synapse Assembly

PTMs for Liprin alpha 1

Learn more about PTMs related to Liprin alpha 1.

Phosphorylation
Acetylation
Dephosphorylation

Bioinformatics Tool for Liprin alpha 1

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