Lipocalin-1 Antibody (223908) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 223908
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Lipocalin-1 Antibody (223908) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Lipocalin-1
  His19-Asp176
  Accession # P31025
• Specificity: Detects human Lipocalin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross‑react with recombinant human Lipocalin-2.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Lipocalin-1 Antibody (223908) [Alexa Fluor® 488]

• LCN1
• lipocalin 1 (tear prealbumin)
• lipocalin 1-like 2
• Lipocalin1
• Lipocalin-1
• MGC71975
• PMFA
• Tear lipocalin
• Tear Prealbumin
• TLC
• TPVon Ebner gland protein
• VEG protein
• VEGP
• VEGPlipocalin 1 (protein migrating faster than albumin, tear prealbumin)

Background

Lipocalin-1, also known as tear prealbumin or von Ebner’s gland protein (VEGP), is encoded by the LCN1 gene (1 - 3). It is a member of the Lipocalin superfamily that binds many different classes of lipophylic chemicals (4). Lipocalin-1 contains three sequence motifs similar to the cystatins, a superfamily of cysteine protease inhibitors (5). In fact, it has been suggested that Lipocalin-1 is a physiological inhibitor of cysteine proteases and plays a role in the control of inflammatory processes in oral and ocular tissues (5). rhLipocalin-1 corresponds to the mature and secreted protein. It is a weak inhibitor of cysteine proteases such as cathepsin V, which is similar to rhCystatin S (R&D Systems, Catalog # 1296-PI).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.