Lgi1 Antibody (S283-7) [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC
• Clone: S283-7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

Lgi1 Antibody (S283-7) [mFluor Violet 500 SE] Summary

• Immunogen: Fusion protein amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse LGI1. Rat: 100% identity (77/77 amino acids identical). Human: 98% identity (76/77 amino acids identical). ~50% identity with LGI2, LGI3 and LGI4.
• Localization: Cell Junction , Golgi Apparatus , Endoplasmic Reticulum
• Specificity: approx 50% identity with LGI2, LGI3 and LGI4.Detects approx 60kDa.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: LGI1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays sequence identity for non-tested species: Human and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Lgi1 Antibody (S283-7) [mFluor Violet 500 SE]

• ADLTE
• ADPAEF
• ADPEAF
• BB130740
• epilepsy, partial
• Epitempin
• Epitempin-1
• EPT
• EPTleucine-rich glioma-inactivated protein 1
• ETL1
• ETL1epitempin-1
• IB1099
• leucine-rich, glioma inactivated 1
• LGI1

Background

The Lgi1 gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobicsegment representing a putative transmembrane domain with the amino terminus located outside the cell. It alsocontains leucine-rich repeats

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LGI1