LEM3 Antibody [HRP]

Product Discontinued

LEM3 Antibody [HRP] Summary

• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1. The immunogen is located within the last 50 amino acids of ANKLE1. Amino Acid Squence: CAGWPPARRRRLGVHL
• Specificity: Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2
• Isotype: IgY
• Clonality: Polyclonal
• Host: Chicken
• Gene: ANKLE1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Peptide affinity purified

Alternate Names for LEM3 Antibody [HRP]

• ANKRD41
• ankyrin repeat and LEM domain containing 1
• ankyrin repeat and LEM domain-containing protein 1
• FLJ39369
• LEM domain containing 6
• LEMD6
• LEM-domain containing protein 3

Background

The LEM3 (ANKLE1) gene encodes an ankyrin repeat and LEM domain-containing protein 1 that in isoform 1 is 615 amino acids long, 66 kDA and in isoform 2 is 575 amino acids long at 62 kDA. LEM3 interacts with the SUMO1, UBC, and RASSF5 genes. It has been linked to diseases such as breast cancer, venous insufficiency, ovarian Cancer, hepatitis b, and legionnaires' disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ANKLE1