KOR Antibody - BSA Free

Immunohistochemistry-Paraffin: KOR Antibody [NLS230] - Analysis of anti-Kappa Opioid Receptor antibody of rat brain, Purkinje neurons at 15 ug/ml.

Product Discontinued

KOR Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 18 amino acid peptide from C-terminus of human KOR.
• Epitope: C-Terminus
• Specificity: Human KOR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Bovine (94%), Rabbit (94%), Bat (94%), Hamster (94%), Canine (94%), Equine (94%), Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OPRK1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 15 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Mouse (89%), Turkey (89%), Chicken (89%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KOR Antibody - BSA Free

• kappa opioid receptor
• kappa-type opioid receptor
• KOR
• K-OR-1
• KOR-1
• Opiate receptor, kappa-1
• opioid receptor, kappa 1
• OPRK
• OPRK1
• Oprk2
• R21

Background

KOR1, an Opioid Receptor, plays a modulatory role in specific aspects of opioid function such as the control of pain. Its endogenous ligand, dynorphin A, is an important neurotransmitter in the central and peripheral nervous systems. KOR1 is believed to mediate sedation, analgesia, and diuresis. KOR1 has been reported to be expressed in the central and peripheral nervous systems, placenta, uterus, breast, and blood. ESTs have been isolated from placenta and prostate libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for KOR Antibody (NLS230). (Showing 1 - 1 of 1 FAQ).

1. Can you please provide me with the exact amino acid sequence that this antibody was raised against?
   • Although the exact immunogen sequence for our Kappa Opioid Receptor antibody with catalogue number NLS230 is proprietary, I can confirm that the antibody was raised against a synthetic 18 amino acid peptide from the C-terminus of the human protein. This sequence shares the following percent identity with other species: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bat, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Guinea pig (94%); Mouse, Rat, Elephant, Turkey, Chicken (89%). A BLAST search has shown it to have no homology with other human proteins.

Bioinformatics

• Gene Symbol: OPRK1
• Entrez:
  • 4986(Human)
• Uniprot:
  • P41145()