Recombinant Human KIR2DS4/CD158i Protein

Product Discontinued

Recombinant Human KIR2DS4/CD158i Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 23-223 of Human KIR2DS4/CD158i
  
  

  Source: E.coli

  Amino Acid Sequence: MEGVHRKPSF LALPGHLVKS EETVILQCWS DVMFEHFLLH REGKFNNTLH LIGEHHDGVS KANFSIGPMM PVLAGTYRCY GSVPHSPYQL SAPSDPLDMV IIGLYEKPSL SAQPGPTVQA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAVRSINGTF QADFPLGPAT HGGTYRCFGS FRDAPYEWSN SSDPLLVSVT GN

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: KIR2DS4
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 22.2 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH7.5)
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human KIR2DS4/CD158i Protein

• CD158 antigen-like family member I
• CD158i antigen
• CD158i
• cl-39
• killer cell immunoglobulin-like receptor 2DS4
• killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail4,nkat8
• killer inhibitory receptor 4-1-2
• KIR antigen 2DS4
• KIR2DS4
• KKA3KIR1D
• MGC120019
• MGC125315
• MGC125317
• MHC class I NK cell receptor
• natural killer cell inhibitory receptor
• Natural killer-associated transcript 8
• NKAT-8
• NKAT8KIR412
• P58 natural killer cell receptor clones CL-39/CL-17
• p58 NK receptor CL-39/CL-17

Background

An activating Killer Cell Ig-like Receptor(KIR, previously called p50 KIR, p50.3, cl39, or KAR-K1), which may recognize class I MHC molecules. The protein coding region of the extracellular domain of KIR2DS4(amino acids 1-202) was cloned into an E. coli expression vector. The extracellular domain of KIR2DS4 was overexpressed as insoluble protein aggregates(inclusion bodies). The recombinant KIR2DS4 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: KIR2DS4