Kallikrein 12 Antibody

Product Discontinued

Kallikrein 12 Antibody Summary

• Immunogen: Residues 236-248 [KYVDWIRMIMRNN] of the human KLK12 protein.
• Specificity: KLK12
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: KLK12
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:500 -1:1000
• Application Notes: This antibody is useful for Western blot, where a band is seen at 26 kDa.
  
  The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 26 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human. Other species have not been tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Kallikrein 12 Antibody

• DKFZp686H1078
• EC 3.4.21
• EC 3.4.21.-
• Kallikrein 12
• Kallikrein-like protein 5
• kallikrein-related peptidase 12
• KLK12
• KLK-L5
• KLKL5kallikrein-12
• KLK-L5MGC42603

Background

Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. A novel KLK gene, KLK12, is expressed in a variety of tissues including salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, thyroid, and trachea. It has applications as a novel cancer biomarker.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Kallikrein 12 Antibody (NB200-137)(1)

Publication using NB200-137

• Morrison MD, Jackson-Boeters L, Khan ZA et al. Identifying Candidate Biomarkers for Pleomorphic Adenoma: A Case-Control Study Head Neck Pathol 2018-08-17 [PMID: 30120721] (IHC-P, Human)

Bioinformatics

• Gene Symbol: KLK12
• Entrez:
  • 43849(Human)