IL-20R alpha Antibody [DyLight 594]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 594

IL-20R alpha Antibody [DyLight 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IL‑20 R alpha
  Val33-Lys253
  Accession # Q6PHB0
• Specificity: Detects mouse IL-20 R alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human (rh) IL-20 R alpha is observed and less than 5% cross-reactivity with rhIL-20 R beta , rhIFN-gamma RI, rhIFN-gamma RII, and rhIL-10 R beta is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: Il22ra2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-20R alpha Antibody [DyLight 594]

• class II cytokine receptor ZCYTOR7
• CRF2-8
• Cytokine receptor class-II member 8
• Cytokine receptor family 2 member 8
• FLJ40993
• IL-20 R alpha
• IL20R alpha
• IL-20R alpha
• IL-20R1
• IL-20R1IL-20 receptor subunit alpha
• IL20RA
• IL-20Ra
• IL-20R-alpha
• interleukin 20 receptor, alpha
• interleukin-20 receptor I
• interleukin-20 receptor subunit alpha
• zcytor7

Background

Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA, is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Il22ra2