Recombinant Human ICAM-5 hIgG-His Protein

SDS-Page: Recombinant Human ICAM-5 hIgG-His Protein [NBP3-05774] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human ICAM-5 hIgG-His Protein Summary

• Description: A recombinant protein hIgG-His-tagged at the C-terminus corresponding to 23-835 amino acids of ICAM-5 (Accession #: NP_003250). Predicted N-terminus: Leu23.
  
  

  Source:HEK293

  Amino acid sequence: LFGLSAVSQE PFWADLQPRV AFVERGGSLW LNCSTNCPRP ERGGLETSLR RNGTQRGLRW LARQLVDIRE PETQPVCFFR CARRTLQARG LIRTFQRPDR VELMPLPPWQ PVGENFTLSC RVPGAGPRAS LTLTLLRGAQ ELIRRSFAGE PPRARGAVLT ATVLARREDH GANFSCRAEL DLRPHGLGLF ENSSAPRELR TFSLSPDAPR LAAPRLLEVG SERPVSCTLD GLFPASEARV YLALGDQNLS PDVTLEGDAF VATATATASA EQEGARQLVC NVTLGGENRE TRENVTIYSF PAPLLTLSEP SVSEGQMVTV TCAAGAQALV TLEGVPAAVP GQPAQLQLNA TENDDRRSFF CDATLDVDGE TLIKNRSAEL RVLYAPRLDD SDCPRSWTWP EGPEQTLRCE ARGNPEPSVH CARSDGGAVL ALGLLGPVTR ALSGTYRCKA ANDQGEAVKD VTLTVEYAPA LDSVGCPERI TWLEGTEASL SCVAHGVPPP DVICVRSGEL GAVIEGLLRV AREHAGTYRC EATNPRGSAA KNVAVTVEYG PRFEEPSCPS NWTWVEGSGR LFSCEVDGKP QPSVKCVGSG GATEGVLLPL APPDPSPRAP RIPRVLAPGI YVCNATNRHG SVAKTVVVSA ESPPEMDEST CPSHQTWLEG AEASALACAA RGRPSPGVRC SREGIPWPEQ QRVSREDAGT YHCVATNAHG TDSRTVTVGV EYRPVVAELA ASPPGGVRPG GNFTLTCRAE AWPPAQISWR APPGALNIGL SSNNSTLSVA GAMGSHGGEY ECAATNAHGR HARRITVRVA GPW

• Source: HEK293
• Protein/Peptide Type: Recombinant Protein
• Gene: ICAM5
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: < 1 EU per 1ug of protein (determined by LAL method)

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 113.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4) and 10% glycerol
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human ICAM-5 hIgG-His Protein

• ICAM5
• ICAM-5
• intercellular adhesion molecule 5
• intercellular adhesion molecule 5, telencephalin
• Telencephalin
• TLCNTelencephalin
• TLNtelencephalin

Background

ICAM-5, also known as telencephalin, is a cell surface glycoprotein belonging to the immunoglobulin superfamily. Human ICAM-5 is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. The tissue of ICAM-5, being expressed only in telencephalic regions of the central nervous system. Like other ICAMs, ICAM-5 binds to the leukocyte integrin LFA-1. Recombinant human ICAM-5, fused to hIgG-His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ICAM5