ICAM-5 Antibody (283607) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: ELISA, ELISA(Cap), ELISA(Det)
• Clone: 283607
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

ICAM-5 Antibody (283607) [mFluor Violet 450 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ICAM-5
  Ala28-Glu570
  Accession # Q9UMF0
• Specificity: Detects human ICAM-5 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CD31, rhCEACAM-1, recombinant mouse (rm) DCC, rhICAM-1, -2, -3, rmICAM-5, rhMAdCAM-1, or rmVCAM-1 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: ICAM5
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ICAM-5 Antibody (283607) [mFluor Violet 450 SE]

• ICAM5
• ICAM-5
• intercellular adhesion molecule 5
• intercellular adhesion molecule 5, telencephalin
• Telencephalin
• TLCNTelencephalin
• TLNtelencephalin

Background

ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ICAM5